There are a few things to consider when naming a podcast:

• Is someone using the name already? That’s important: do your research; at the very least, go to the iTunes store and check.
• Is the name such a common word or phrase that your show will not appear in the first thousand pages of Google results?
• Is the name a riff on a pre-existing title, like That American Life, so no matter how successful your show gets, it will never completely be your own, and always a bit of a parasite on someone else's thing?
• Is it a riff on ‘pod’ or ‘cast’? That was already stale when I was starting my first podcast nearly ten years ago. Resist the pod puns!